1.1 Abrasives: Dosage is 40%-55%. Common abrasives include:
Calcium carbonate (there light, heavy and natural three types, among which the cost of heavy calcium carbonate is the cheapest), calcium hydrogen phosphate dihydrate (the cost is a little higher, with which the toothpaste is bright and clean).
Calcium pyrophosphate: There are α, β, γ three types. β and γ types inter-crystallizes. Compatible with fluoride products. Have good soft abrasive.
Hydrated aluminum: One of the ideal abrasives. Good compatibility with fluoride calcium pyrophosphate products.
Silicon dioxide: Precipitated silicon dioxide has good compatibility with fluoride products. When its refraction index is the same as that of the liquid refraction index, the toothpaste body is transparent.
Water-insoluble sodium metaphosphate: Compatible with fluoride products.
Sodium aluminum silicate: The mole ratio between SiO2 and Al2O3 should be 45:7 at least. Can add fluoride product (especially disodium monofluorophosphate), or chlorhexidine
1.2 Moisturizers (Excipient): Usual usage is 20%-30%. Dosage for transparent toothpaste is 75%. Common moisturizers include glycerol, sorbitol, propylene glycol, poly(ethylene glycol). Besides, DL-Xylose has a sweet taste, and effect of moisturizing and anti-caries.
1.3 Forming Agent: Usage is 2%-3%. Often use a surfactant.
1.4 Binding Agent: Prevent the separation of powder and liquid. Endow toothpaste proper viscoelasticity and shape. Dosage is 1%-2%. Common binders have CMC, HEC, carbopol, poly(vinyl alcohol), xanthan gum, carrageenan, silicon dioxide, and complex clay.
1.5 Perfume: Dosage is 1%-2%. Common perfumes are spearmint oil, mint oil, holly oil, clove oil, fennel oil, cinnamon oil, etc.
1.6 Sweeteners: Dosage is 0.05%-0.25%. Commonly use saccharin sodium
1.7 Preservative: Dosage is 0.03%-0.1%. Often use methylparaben, ethyl and propyl ester
1.8 Corrosion Inhibitor: Commonly use sodium silicate and colloidal silicon dioxide to resist alkaline toothpaste, avoiding the corrosion of the aluminum tube.
1.9 Anti-Caries Substances: Commonly use disodium monofluorophosphate, then add sodium fluoride.
1.10 Anti-Periodontitis Substances: Select quaternary ammonium compounds, such as alkyl quaternary ammonium sulphosuccinic acid ester (inhibit bacterial plaque and dental calculus), zinc citrate, sodium polyphosphatem, chlorhexidine, etc and Chinese herbal medicines.
1.11 Anti-Dentin Hypersensitivity (when the tooth receives stimulation from cold, hot, acid, sweet and mechanical, etc): Commonly add sodium chloride, formaldehyde, zinc chloride, silver nitrate, strontium chloride and so on.
There are so many kinds of a binding agent of toothpaste. Comparing the cost performance of CMC with other binding agents, CMC is a widely used good binder.
CMC is basically compatible with a cellulolytic enzyme, to prevent viscosity from decreasing. CMC solution has pseudo-plasticity with excellent dispersing ability. It can reduce mechanical wear. CMC gum is bright, elastic and exquisite. The gum, not dehydration, not coarse after long term storage.
Customized toothpaste grade CMC produced by Fortune Biotech is featured by high substituting degree, high purity, and stable viscosity. Its even substitution results in good temperature endurance and salt tolerance.
Toothpaste Grade CMC products manufactured by Fortune Biotech has good fineness. Weight from 60 mesh to 200 mesh are available. Fast dissolving speed. It can dissolve rapidly in a common emulsifier within 5 minutes.
For common toothpaste, we can select CMC IH9. Dosage is 0.8%-1.2%. For top-grade toothpaste, we can use CMC IH9, IH10. Separate dosage is 1.0%-1.2%. Dosage is 0.6%-1.0% when compounding with other gum.